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Liver Cirrhosis Symptoms, Causes, Treatment & Cure


Liver Cirrhosis Symptoms, Causes, Treatment & Cure

Liver Cirrhosis Symptoms, Causes, Treatment & Cure

In this article, we will explain the stages of cirrhosis of the liver and the causes that lead to cirrhosis, and we will talk about the different lines of treatment for liver cirrhosis including stem cell transplant and also herbal treatment. Get more information on the latest news related to liver cirrhosis.

What Is Liver Cirrhosis?

Liver cirrhosis occurs when scar tissue builds up inside the liver. Scarring happens because of damage to the liver caused by alcohol abuse, hepatitis C infection, or autoimmune diseases.

Causes Of Liver Cirrhosis:

There are many reasons, including:

1- Hepatitis B or C viruses

2- fatty liver

3- alcohol addiction

4- Autoimmune hepatitis

5- Use of some medicines for a long time

Diagnosis of the degree of liver fibrosis:

This can be done either with a liver biopsy or recently the Fibroscan.

What is a Fibroscan device?

It is a device like a sonar device in shape that measures the percentage of fibers in the liver and gives it degrees

F0 There is no fiber in the liver (normal liver)

F1 is a simple grade of liver fiber

F2 is a medium grade of liver fiber

F3 is a severe degree of liver fiber

F4 cirrhosis stage

A modern version of the Fibroscan device has appeared that can also measure the percentage of fat in the liver and give it degrees as well

S0 There is no fat in the liver (normal liver)

S1 is a small percentage of liver fat

S2 is an average percentage of liver fat

S3 is very high in liver fat

What is the difference between cirrhosis and liver fibrosis?

cirrhosis is one thing and liver fibers are another thing, meaning that the accumulation of fibers leads to reaching the stage of cirrhosis of the liver F4.

Stages of F4 cirrhosis and their symptoms:

We can divide F4 cirrhosis into two stages based on several indicators such as liver function, ascites in the abdomen, or hepatic coma.

In the stage of early fibrosis (compensated cirrhosis), in which the liver functions are good and there is no ascites in the abdomen, hepatic coma, or yellowing of the eyes, where the person is almost normal, he may only suffer from constant fatigue or swelling of the feet or bruises in the body with any collision.

The stage of late cirrhosis (decompensated cirrhosis), in which there is a deterioration in liver function, ascites in the abdomen, recurrent coma, yellowing of the eyes, and vomiting blood due to bleeding of esophageal varices.

What is the treatment for cirrhosis of the liver:

Treatment of Compensated cirrhosis:

Two basic conditions must be present

First: Knowing the cause of cirrhosis and treating it, for example, treating hepatitis viruses or treating fatty liver, etc.

Second: The liver is in the early cirrhosis stage

If these two conditions are met and the cause of cirrhosis of the liver is treated, then the percentage of liver fibers decreases significantly over time, which leads to the decline of cirrhosis to lower degrees such as F3, F2,

Treatment of advanced or late-stage (decompensated) cirrhosis of the liver:

In this case, the best treatment is liver transplantation, in which the cirrhotic liver is replaced with a liver lobe from a healthy donor. Within several months, the transplanted lobe will grow into a complete liver. The success rate of this operation is very high, more than 90%.

But in the absence of liver grafts, we can treat the cause of fibrosis, which may lead to a significant improvement in liver function, in addition to treating complications of fibrosis such as ascites, jaundice, and esophageal varices.

Follow-up of a patient with cirrhosis of the liver:

This is a very important point, as many patients, after treating the cause of cirrhosis, think that their liver has become healthy and neglect the follow-up until they wake up from a nightmare such as bleeding esophageal varices or cancerous liver tumors. Live function tests and liver tumor marker analysis, in addition to ultrasound examination to detect any problem in its infancy, for example, cancerous liver tumors are easy to treat if they are discovered and are in a small size, then they can be treated by various means such as radiofrequency, microwave, chemoembolization or surgery.

The cirrhotic patient also needs to have an endoscopy on the stomach:

- In the absence of esophageal varices, it is recommended to repeat the endoscopy after 3 years

- In the case of small varicose veins, drug treatment is recommended to reduce the pressure of the hepatic portal vein to prevent these varicose veins from increasing in size with a follow-up endoscopy every year.

- In the event of large varicose veins in the esophagus, it is recommended to perform varicose veins ligation sessions to get rid of them with drug treatment to reduce the pressure of the hepatic portal vein.

Are there any new medicines to treat cirrhosis of the liver?

Indeed, there are many drugs in advanced stages of research to treat liver cirrhosis, and many of them have given promising results, but none of them takes FDA approval, waiting for further research.

Stem cell transplant:

It is a new technique, where cell able to differentiate into liver cells was taken from the patient’s bone marrow or from a fetus’s placenta or umbilical cord. Then these cells were injected inside the patient’s body either through an IV line or by catheter into the hepatic artery or directly inside the spleen. Over time, the cells populate the liver to take over the function of the injured liver cells.

Clinical studies revealed improvement in the liver function of the patients, however, this improvement was only short-term as the injected cells could not survive for a long time, and many efforts are done now to solve the problems facing stem cell transplants.

Herbal treatment of liver cirrhosis:


Silymarin is an extract of the milk thistle (Silybum marianum) that contains a variety of flavonoids. It has long been used as a supportive, hepatoprotective medication in patients with liver cirrhosis, chronic inflammatory, and toxic liver diseases; however, studies have failed to demonstrate any benefits of Silymarin in the treatment of liver cirrhosis.


Curcumin, the active compound of Curcuma longa has been investigated in several medical diseases and reported to exert tumor preventive, antiviral, and anti-inflammatory effects in chronic liver disease, however, more studies are needed to demonstrate its efficiency in the treatment of liver cirrhosis.


Resveratrol is a natural antioxidant that can be found in a wide variety of plants. Its use in patients with chronic liver diseases revealed improvement in the degree of inflammation and the liver enzymes but not the degree of fibrosis.

Is the Laennec effective in the treatment of liver cirrhosis?

Laennec is a placental extract containing a variety of growth factors, including HGF (hepatocyte growth factor), which promotes the proliferation of hepatic parenchymal cells and thus aids in the recovery of a damaged liver.

It is administered once daily via IM or SC injection. Clinical trials failed to demonstrate any reduction in liver fibrosis in patients treated with Laennec.

Liver Cirrhosis Prevention Tips:

Prevention of hepatitis viruses:

Vaccination in case of virus B

Avoid using shared needles or syringes

Avoid unsafe sex which may transmit hepatitis B.

Screening of pregnant mothers for hepatitis B virus, because it can transmit to the baby through the placenta.

Treatment of HBV and HCV by the available medications

Prevention and treatment of fatty liver

Avoid excess alcohol intake

Avoid unwise use of the medications


 It is that the treatment of cirrhosis of the liver is possible, provided that the cirrhosis is in an early stage (compensated cirrhosis of the liver) and that the cause of the cirrhosis is known in this case. In the case of uneven fibrosis, the optimal treatment is liver transplantation. If it is not available, the alternative is to treat the cause to maintain the existing percentage of fibrosis and not progress, in addition to treating the complications of cirrhosis. In all cases, whether the cirrhosis is compensated or decompensated, it is necessary to follow up periodically for early detection of any complications such as liver tumors, esophageal varices, ascites, and early treatment.